5 Best Pharmacies in Downtown, Tucson AZ

This guide lists five pharmacies in Downtown, Tucson, AZ, ranked by Google rating weighted by how many people left one. Fourteen qualifying businesses were considered. Each entry includes hours, address, accessibility and service details from Google, along with themes that reviewers mention, such as clear medication guidance, text alerts for prescriptions and vaccinations. Pharmacy hours and services can change, so check before visiting, and call ahead for specialty prescriptions or delivery questions.

The list at a glance

  1. 1Acacia Apothecary and Wellness Compounding Pharmacy-Orange Grove★ 4.7 · 85 reviews
  2. 2TMC Pharmacy★ 4.6 · 72 reviews
  3. 3Desert Life Pharmacy★ 4.7 · 39 reviews
  4. 4Walgreens Specialty Pharmacy★ 4.7 · 31 reviews
  5. 5CVS Pharmacy★ 4.7 · 23 reviews
#1

Acacia Apothecary and Wellness Compounding Pharmacy-Orange Grove

★ 4.7 (85 Google reviews)Pharmacy

Representative photo, not of this business.

Acacia Apothecary and Wellness Compounding Pharmacy-Orange Grove is at 1845 W Orange Grove Rd and is rated 4.7 from 85 Google reviews. Weekday hours run from 9:30 am to 5:30 pm, Saturday morning until 12:30 pm, and it is closed on Sundays. Google lists wheelchair-accessible parking and entrance. Reviewers mention pharmacists who explain how to take medication and answer questions clearly. Text alerts for refills and ready prescriptions are praised. One reviewer says a pet's prescription was prepared on time, with helpful instructions.

Best for: Clear medication guidance and text alerts
Address
1845 W Orange Grove Rd #115, Tucson, AZ 85704, United States
Hours
Fri 9:30 am–5:30 pm; Mon 9:30 am–5:30 pm; Sat 9:30 am–12:30 pm; Sun Closed; Thu 9:30 am–5:30 pm; Tue 9:30 am–5:30 pm; Wed 9:30 am–5:30 pm
#2

TMC Pharmacy

★ 4.6 (72 Google reviews)Pharmacy

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TMC Pharmacy is at 5310 E Grant Rd and holds a 4.6 average from 72 Google reviews. Weekday hours run from 8 am to 9 pm, and weekends are open from 9 am to 3 pm. Google lists wheelchair-accessible parking and entrance. Reviewers describe the team as professional and courteous, and say prescriptions are filled promptly. Some mention that the phone gets answered and that the pharmacy usually has medicines that other stores are short on. A reviewer also says staff helped them find ways to lower prescription costs.

Best for: Reliable refills and hard-to-find medications
Address
5310 E Grant Rd, Tucson, AZ 85712, United States
Hours
Fri 8 am–9 pm; Mon 8 am–9 pm; Sat 9 am–3 pm; Sun 9 am–3 pm; Thu 8 am–9 pm; Tue 8 am–9 pm; Wed 8 am–9 pm
#3

Desert Life Pharmacy

★ 4.7 (39 Google reviews)Pharmacy

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Desert Life Pharmacy is at 63675 E SaddleBrooke Blvd S and is rated 4.7 from 39 Google reviews. Google lists it as a women-owned small business that offers delivery and medication disposal. Weekday hours are split around a midday break, Saturday hours run until 2 pm, and it is closed on Sundays. Reviewers describe fast, professional service and say a pharmacist took time with them during a busy period. One reviewer says staff stayed to help near closing time when they were in urgent need.

Best for: Attentive local service and delivery
Address
63675 E SaddleBrooke Blvd S, Tucson, AZ 85739, United States
Hours
Fri 8 am–12 pm, 1–5 pm; Mon 8 am–12 pm, 1–5 pm; Sat 10 am–2 pm; Sun Closed; Thu 8 am–12 pm, 1–5 pm; Tue 8 am–12 pm, 1–5 pm; Wed 8 am–12 pm, 1–5 pm
#4

Walgreens Specialty Pharmacy

★ 4.7 (31 Google reviews)Pharmacy

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Walgreens Specialty Pharmacy is at 1830 E Broadway Blvd, Suite 136, and is rated 4.7 from 31 Google reviews. Hours run on weekdays with a midday break, and the pharmacy is closed on weekends. Google lists delivery, in-store pick-up and LGBTQ+ friendly service, with wheelchair-accessible parking and entrance. Reviewers mention a specialty eye drop that was shipped with good expertise. One describes a same-day request where staff phoned other stores to fill a second prescription. Quick, friendly pick-up and reliable delivery come up often.

Best for: Specialty prescriptions with delivery
Address
1830 E Broadway Blvd Ste 136, Tucson, AZ 85719, United States
Hours
Fri 8:30 am–1:30 pm, 2–5 pm; Mon 8:30 am–1:30 pm, 2–5 pm; Sat Closed; Sun Closed; Thu 8:30 am–1:30 pm, 2–5 pm; Tue 8:30 am–1:30 pm, 2–5 pm; Wed 8:30 am–1:30 pm, 2–5 pm
#5

CVS Pharmacy

★ 4.7 (23 Google reviews)Pharmacy

Representative photo, not of this business.

CVS Pharmacy is at 6370 N Campbell Ave, Suite 120, and is rated 4.7 from 23 Google reviews. Weekday hours run from 9 am to 8 pm with a midday break, and weekend hours are shorter. Google lists wheelchair-accessible parking and an accessible entrance. Reviewers say lines usually move quickly and that the staff is helpful and friendly. One mentions booking a vaccination online and receiving it from a pharmacist at the scheduled time. Others value fast replies to messages and text alerts when prescriptions are ready.

Best for: Vaccinations and quick prescription pick-up
Address
6370 N Campbell Ave #120, Tucson, AZ 85718, United States
Hours
Fri 9 am–1:30 pm, 2–8 pm; Mon 9 am–1:30 pm, 2–8 pm; Sat 10 am–1:30 pm, 2–5 pm; Sun 10 am–1:30 pm, 2–5 pm; Thu 9 am–1:30 pm, 2–8 pm; Tue 9 am–1:30 pm, 2–8 pm; Wed 9 am–1:30 pm, 2–8 pm

How we made this list

We looked at 14 pharmacies in Downtown, Tucson AZ with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.

Tips before you go

Frequently asked questions

Which is the highest-rated pharmacy on this list?

Acacia Apothecary and Wellness Compounding Pharmacy-Orange Grove ranks first, with a Google rating of 4.7 from 85 reviews. TMC Pharmacy is second at 4.6 from 72 reviews.

Which pharmacies in Downtown, Tucson AZ are open late?

None of these stays open past midnight. The latest to close is TMC Pharmacy, at 9 pm.

Which of these have free parking?

Google lists free parking for Walgreens Specialty Pharmacy.

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