5 Best Pharmacies in Downtown, Spokane WA
Updated 11 October 2026 · 9 pharmacies in Downtown, Spokane WA considered · Ranked from Google ratings
This list covers pharmacies in Downtown Spokane, WA, ranked by Google rating weighted by the number of reviews. Nine qualifying businesses were considered. Reviews point to different strengths, including quick refills, compounded medications and personal attention, and also to occasional complaints about delays and communication. The list is a starting point for choosing where to fill a prescription, and it is worth checking hours and insurance before you go.
#1
MultiCare Rockwood Clinic Pharmacy
★ 4.6 (281 Google reviews)Pharmacy
Representative photo, not of this business.
MultiCare Rockwood Clinic Pharmacy has a 4.6 rating from 281 reviews, at 300 E 5th Ave. It is open Monday through Friday from 8 am, with Saturday hours from 8:30 am to 2:30 pm and Sunday closed. Delivery, in-store shopping, on-site services and medication disposal are listed. Reviewers mention prescriptions filled quickly after urgent care and a pharmacist who is thorough and calls about any issues. Others describe lost medications and slow refills.
Best for: Clinic-linked prescriptions and medication disposal
- Address
- 300 E 5th Ave, Spokane, WA 99202, United States
- Hours
- Fri 8 am–6:30 pm; Mon 8 am–6:30 pm; Sat 8:30 am–2:30 pm; Sun Closed; Thu 8 am–6:30 pm; Tue 8 am–6:30 pm; Wed 8 am–6:30 pm
#2
Koru Pharmacy
★ 4.6 (115 Google reviews)Pharmacy
Representative photo, not of this business.
Koru Pharmacy has a 4.6 rating from 115 reviews, at 1802 N Monroe St. It is open weekdays from 8:30 am to 6 pm and Saturday from 9 am to 1 pm, and closed on Sundays. Attributes include small business, delivery, on-site services and medication disposal. Reviewers describe a compounding pharmacy that makes customized medications for people and pets, and mention staff who found a way to fill a hard-to-get prescription after an emergency room visit.
Best for: Compounded and custom medications
- Address
- 1802 N Monroe St, Spokane, WA 99205, United States
- Hours
- Fri 8:30 am–6 pm; Mon 8:30 am–6 pm; Sat 9 am–1 pm; Sun Closed; Thu 8:30 am–6 pm; Tue 8:30 am–6 pm; Wed 8:30 am–6 pm
#3
Hart and Dilatush Pharmacy
★ 4.7 (55 Google reviews)Pharmacy
Representative photo, not of this business.
Hart and Dilatush Pharmacy has a 4.7 rating from 55 reviews, at 601 W Riverside Ave, Suite 140. It is open Monday through Friday from 8 am to 5 pm and closed on weekends. Wheelchair-accessible parking and entrance are listed. Reviewers describe a small pharmacy with kind, familiar service and a team that asks how customers are doing. Some report a long delay in filling prescriptions after a home health transfer.
Best for: Personal attention from a small team
- Address
- 601 W Riverside Ave #140, Spokane, WA 99201, United States
- Hours
- Fri 8 am–5 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–5 pm; Tue 8 am–5 pm; Wed 8 am–5 pm
#4
CHAS Denny Murphy Pharmacy
★ 4.7 (50 Google reviews)Pharmacy
Representative photo, not of this business.
CHAS Denny Murphy Pharmacy has a 4.7 rating from 50 reviews, at 1001 W 2nd Ave. It is open Monday through Friday from 7:30 am to 6 pm and Saturday until 5 pm, and closed on Sundays. Delivery, in-store pick-up, medication disposal, LGBTQ+ friendly and transgender safe space are listed. Reviewers mention quick and efficient visits, a well organized and clean building. Some excerpts describe dental care rather than pharmacy service, so they say little about prescriptions.
Best for: Quick, well organized visits
- Address
- 1001 W 2nd Ave, Spokane, WA 99201, United States
- Hours
- Fri 7:30 am–6 pm; Mon 7:30 am–6 pm; Sat 7:30 am–5 pm; Sun Closed; Thu 7:30 am–6 pm; Tue 7:30 am–6 pm; Wed 7:30 am–6 pm
#5
Lidgerwood Owl Pharmacy
★ 4.8 (28 Google reviews)Pharmacy
Representative photo, not of this business.
Lidgerwood Owl Pharmacy has a 4.8 rating from 28 reviews, at 220 E Rowan Ave, Suite 170. It is open weekdays from 9 am to 5 pm and closed on weekends. Wheelchair-accessible parking and entrance are listed. Reviewers say medications are processed quickly, insurance is handled correctly, and staff look for alternatives when a drug is out of stock. One review describes an unprofessional interaction with a staff member over mask rules, so experiences vary.
Best for: Insurance help and quick refills
- Address
- 220 E Rowan Ave #170, Spokane, WA 99207, United States
- Hours
- Fri 9 am–5 pm; Mon 9 am–5 pm; Sat Closed; Sun Closed; Thu 9 am–5 pm; Tue 9 am–5 pm; Wed 9 am–5 pm
How we made this list
We looked at 9 pharmacies in Downtown, Spokane WA with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, CHAS Denny Murphy Pharmacy opens at 7:30 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated pharmacy on this list?
MultiCare Rockwood Clinic Pharmacy ranks first, with a Google rating of 4.6 from 281 reviews. Koru Pharmacy is second at 4.6 from 115 reviews.
Which pharmacies in Downtown, Spokane WA are open late?
None of these stays open past midnight. The latest to close is MultiCare Rockwood Clinic Pharmacy, at 6:30 pm.
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