5 Best Dental Clinics in Downtown, Sioux Falls SD
Updated 11 October 2026 · 22 dental clinics in Downtown, Sioux Falls SD considered · Ranked from Google ratings
This list covers dental clinics in the Downtown Sioux Falls, SD area for people looking for a dentist for cleanings, exams or treatment. Businesses were ranked by Google rating, weighted by how many people left one, from a pool of 22 qualifying clinics. The ordering comes only from those ratings and review counts. Each entry below lists the address, opening hours, accessibility features and payment options from its Google listing, with review excerpts that describe what some patients have said. Call ahead to confirm current hours and availability.
#1
Karmazin Dental
★ 5 (844 Google reviews)Dentist
Representative photo, not of this business.
Karmazin Dental is a dentist in Sioux Falls with a 5-star Google rating from 844 reviews. The office is listed at 5701 S Remington Pl and is open Monday, Tuesday, Wednesday and Thursday from 7 am to 3 pm. Appointments are recommended and the listing shows wheelchair-accessible parking, entrance, seating and toilet, plus free parking, on-site parking and payment plans. Reviewers mention a welcoming front desk, a clean and modern office, and explanations that are clear during appointments.
Best for: Accessible care and payment plan options
- Address
- 5701 S Remington Pl, Sioux Falls, SD 57108, United States
- Hours
- Fri Closed; Mon 7 am–3 pm; Sat Closed; Sun Closed; Thu 7 am–3 pm; Tue 7 am–3 pm; Wed 7 am–3 pm
#2
Falls Dental
★ 5 (683 Google reviews)Dentist
Representative photo, not of this business.
Falls Dental has a 5 rating from 683 reviews and is at 5100 S Cliff Ave. Hours run Monday, Tuesday, Wednesday and Thursday from 8 am to 5 pm, with Friday open 8 am to 2 pm. The listing shows wheelchair-accessible parking, entrance, seating and toilet. Reviewers mention a calm, unrushed experience for patients with dental anxiety, staff who go out of their way for families, and a front desk team that helps new patients book quickly.
Best for: Families and patients with dental anxiety
- Address
- 5100 S Cliff Ave, Sioux Falls, SD 57108, United States
- Hours
- Fri 8 am–2 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–5 pm; Tue 8 am–5 pm; Wed 8 am–5 pm
#3
Dental Essence
★ 4.9 (1,051 Google reviews)Dentist
Representative photo, not of this business.
Dental Essence is a dentist at 3610 S Western Ave with a 4.9 rating from 1,051 reviews. Hours run Monday and Thursday 8 am to 5 pm, Tuesday and Wednesday 7 am to 4 pm, and Friday 7 am to 3 pm, with weekends closed. The listing shows wheelchair-accessible parking, entrance and toilet. Reviewers mention a clean, stylish waiting room, hygienists who are kind and friendly, and a team that does not push unneeded services.
Best for: Patients who want a relaxed, no-pressure visit
- Address
- 3610 S Western Ave, Sioux Falls, SD 57105, United States
- Hours
- Fri 7 am–3 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–5 pm; Tue 7 am–4 pm; Wed 7 am–4 pm
#4
Kappenman Family Dental
★ 4.9 (1,018 Google reviews)Dentist
Representative photo, not of this business.
Kappenman Family Dental is at 5704 W 41st St and holds a 4.9 rating from 1,018 reviews. Hours are Monday, Tuesday, Wednesday and Thursday 8 am to 5 pm, and Friday 8 am to 4 pm, with weekends closed. The listing includes on-site services, cosmetic and sedation dentistry, wheelchair-accessible parking, entrance and toilet, and appointments are recommended. Reviewers mention a family feel that long-time patients value, friendly front desk staff, and doctors who explain procedures clearly.
Best for: Families and sedation or cosmetic needs
- Address
- 5704 W 41st St, Sioux Falls, SD 57106, United States
- Hours
- Fri 8 am–4 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–5 pm; Tue 8 am–5 pm; Wed 8 am–5 pm
#5
South Western Dental
★ 4.9 (780 Google reviews)Dentist
Representative photo, not of this business.
South Western Dental is at 5201 S Western Ave with a 4.9 rating from 780 reviews. It is open Monday, Tuesday, Wednesday, Thursday and Friday from 7 am to 5 pm, and closed on weekends. The listing shows on-site services, emergency services, pediatric care, cosmetic dentistry, appointments recommended, wheelchair-accessible parking, entrance and toilet, and free parking. Reviewers mention a professional but comfortable atmosphere, thorough cleanings and exams, and hygienists who remember patients' details.
Best for: Families, kids and routine cleanings
- Address
- 5201 S Western Ave, Sioux Falls, SD 57108, United States
- Hours
- Fri 7 am–5 pm; Mon 7 am–5 pm; Sat Closed; Sun Closed; Thu 7 am–5 pm; Tue 7 am–5 pm; Wed 7 am–5 pm
How we made this list
We looked at 22 dental clinics in Downtown, Sioux Falls SD with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, Karmazin Dental opens at 7 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated dental clinic on this list?
Karmazin Dental ranks first, with a Google rating of 5 from 844 reviews. Falls Dental is second at 5 from 683 reviews.
Which dental clinics in Downtown, Sioux Falls SD are open late?
None of these stays open past midnight. The latest to close is Falls Dental, at 5 pm.
Which of these have free parking?
Google lists free parking for Karmazin Dental and South Western Dental.
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