5 Best Clinics in Midland TX

This list covers five clinics serving Midland, TX and nearby Odessa, for anyone who needs emergency care, urgent care or an orthopedic visit. Businesses were ranked by Google rating weighted by how many people left one, and only places with at least 300 reviews qualified. Fifteen qualifying businesses were considered. Two entries are in Odessa, so check the address before you travel. Each blurb summarizes the Google profile and the themes reviewers mention.

The list at a glance

  1. 1Priority ER Care Odessa - 24 Hours Emergency Room - No Wait Time★ 5 · 2,058 reviews
  2. 2OrthoMidland★ 4.9 · 2,498 reviews
  3. 3WesTex Urgent Care★ 4.9 · 1,223 reviews
  4. 4SignatureCare Emergency Center : Emergency Room★ 4.8 · 2,633 reviews
  5. 5SignatureCare Emergency Center : Emergency Room★ 4.8 · 2,482 reviews
#1

Priority ER Care Odessa - 24 Hours Emergency Room - No Wait Time

★ 5 (2,058 Google reviews)Emergency room

Representative photo, not of this business.

This emergency room in Odessa is rated 5 from 2,058 Google reviews and is open 24 hours a day. Google lists it under emergency room with wheelchair-accessible parking, entrance, seating and toilet. No price range is listed. Reviewers describe short waits to be called back to a room, a very clean facility, and a front desk team that checks patients in quickly. Several reviewers say staff were kind to children and worried families.

Best for: Round-the-clock emergency care in Odessa
Address
3800 E 42nd St Ste 105, Odessa, TX 79762, United States
Hours
daily Open 24 hours
#2

OrthoMidland

★ 4.9 (2,498 Google reviews)Orthopedic clinic

Representative photo, not of this business.

OrthoMidland is an orthopedic clinic rated 4.9 from 2,498 Google reviews, located on Andrews Highway in Midland. It is open Monday through Friday from 8 am to 5 pm and closed on weekends. Google lists wheelchair-accessible parking, entrance and toilet. Reviewers say the doctors listen carefully and explain each step, and that one practice team saw a patient urgently. A few mentioned a front desk that felt less welcoming, and one disliked a paperwork fee.

Best for: Weekday orthopedic appointments
Address
4304 Andrews Hwy, Midland, TX 79703, United States
Hours
Fri 8 am–5 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–5 pm; Tue 8 am–5 pm; Wed 8 am–5 pm
#3

WesTex Urgent Care

★ 4.9 (1,223 Google reviews)Urgent care center

Representative photo, not of this business.

WesTex Urgent Care is rated 4.9 from 1,223 Google reviews and is located on Eastridge Road in Odessa. It is open weekdays from 7:30 am to 7:30 pm and on weekends from 9 am to 5 pm. Google lists wheelchair-accessible parking, entrance, seating and toilet. Reviewers mention fast check-in, online scheduling for early appointments, and staff who explain results. One review says visit notes are emailed as a digital copy afterward.

Best for: Urgent care with long weekday hours
Address
6950 Eastridge Rd, Odessa, TX 79765, United States
Hours
Fri 7:30 am–7:30 pm; Mon 7:30 am–7:30 pm; Sat 9 am–5 pm; Sun 9 am–5 pm; Thu 7:30 am–7:30 pm; Tue 7:30 am–7:30 pm; Wed 7:30 am–7:30 pm
#4

SignatureCare Emergency Center : Emergency Room

★ 4.8 (2,633 Google reviews)Emergency room

Representative photo, not of this business.

This Midland emergency center on West Wadley Avenue is rated 4.8 from 2,633 Google reviews and is open 24 hours a day. Google lists on-site services, an assistive hearing loop, wheelchair access, gender-neutral toilets and card or mobile payments. No price range is listed. Reviewers mention friendly, efficient staff, quick triage, and nurses who made patients feel cared for during difficult visits.

Best for: 24-hour emergency care in Midland
Address
5409 W Wadley Ave, Midland, TX 79707, United States
Hours
daily Open 24 hours
#5

SignatureCare Emergency Center : Emergency Room

★ 4.8 (2,482 Google reviews)Emergency room

Representative photo, not of this business.

This emergency center on North Grandview Avenue in Odessa is rated 4.8 from 2,482 Google reviews and is open 24 hours a day. Google lists an assistive hearing loop and wheelchair-accessible parking, entrance, seating and toilet. No price range is listed. Reviewers mention waits of under five minutes to reach a room, a doctor who answered every question, and a CT scan explained in detail. Some say a nurse seemed less friendly than the rest of the team.

Best for: 24-hour emergency care in Odessa
Address
2731 N Grandview Ave, Odessa, TX 79762, United States
Hours
daily Open 24 hours

How we made this list

We looked at 15 clinics in Midland TX with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by weighted Google rating across the city, 300 reviews minimum. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.

Tips before you go

Frequently asked questions

Which is the highest-rated clinic on this list?

Priority ER Care Odessa - 24 Hours Emergency Room - No Wait Time ranks first, with a Google rating of 5 from 2,058 reviews. OrthoMidland is second at 4.9 from 2,498 reviews.

Which clinics in Midland TX are open late?

Priority ER Care Odessa - 24 Hours Emergency Room - No Wait Time, SignatureCare Emergency Center : Emergency Room and SignatureCare Emergency Center : Emergency Room are listed as open 24 hours.

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