5 Best Pharmacies in Downtown, Lincoln NE
Updated 11 October 2026 · 13 pharmacies in Downtown, Lincoln NE considered · Ranked from Google ratings
This list ranks five pharmacies in Downtown Lincoln, Nebraska by Google rating, weighted by how many people left one. Thirteen qualifying businesses were considered. Each entry gives the address, hours and listed services, along with what reviewers mention about prescriptions, refills and staff knowledge. Pharmacy services and hours can change, so confirm them with the store before you visit or transfer a prescription.
#1
Lincoln Pharmacy
★ 4.7 (67 Google reviews)Pharmacy
Representative photo, not of this business.
Lincoln Pharmacy is a pharmacy at 3300 A St, Suite 100, rated 4.7 from 67 reviews. It is open Monday to Friday from 8:30 am to 6 pm and on Saturday from 10 am to 4 pm, and it is closed on Sunday. Reviewers mention pill packs that are easy to manage, refill reminders and alerts about manufacturing issues. Reviewers describe the staff as knowledgeable and personable, and one says the pharmacy is locally owned.
Best for: Pill packs and reorder reminders
- Address
- 3300 A St Ste 100, Lincoln, NE 68510, United States
- Hours
- Fri 8:30 am–6 pm; Mon 8:30 am–6 pm; Sat 10 am–4 pm; Sun Closed; Thu 8:30 am–6 pm; Tue 8:30 am–6 pm; Wed 8:30 am–6 pm
#2
Pharmacy Solutions
★ 4.6 (95 Google reviews)Pharmacy
Representative photo, not of this business.
Pharmacy Solutions is a pharmacy at 5750 Hidcote Dr, rated 4.6 from 95 reviews. It is open Monday, Wednesday, Thursday and Friday from 8:30 am to 5 pm, on Tuesday until 6 pm, and it is closed on weekends. Reviewers mention knowledgeable staff who give advice on supplements for digestion, skin and hormones. Reviewers say the team greets them warmly and helps them find products. Google lists wheelchair-accessible parking, entrance, seating and toilet.
Best for: Supplements and product guidance
- Address
- 5750 Hidcote Dr, Lincoln, NE 68516, United States
- Hours
- Fri 8:30 am–5 pm; Mon 8:30 am–5 pm; Sat Closed; Sun Closed; Thu 8:30 am–5 pm; Tue 8:30 am–6 pm; Wed 8:30 am–5 pm
#3
Wellness Pharmacy - Compounding
★ 5 (23 Google reviews)Pharmacy
Representative photo, not of this business.
Wellness Pharmacy - Compounding is a pharmacy at 4640 Champlain Dr, Suite 113, rated 5 from 23 reviews. It is open Monday to Friday from 9 am to 5:30 pm, and it is closed on weekends. Reviewers mention compounded liquid medication, including for a pet, delivered on time for refills. Reviewers also praise staff who helped with a prescription after a prior doctor retired. Google lists wheelchair-accessible parking and entrance.
Best for: Compounded and liquid medications
- Address
- 4640 Champlain Dr #113, Lincoln, NE 68521, United States
- Hours
- Fri 9 am–5:30 pm; Mon 9 am–5:30 pm; Sat Closed; Sun Closed; Thu 9 am–5:30 pm; Tue 9 am–5:30 pm; Wed 9 am–5:30 pm
#4
CVS Pharmacy
★ 4.7 (32 Google reviews)Pharmacy
Representative photo, not of this business.
CVS Pharmacy at 333 N 48th St is rated 4.7 from 32 reviews. It is open Monday to Friday from 9 am to 1:30 pm and 2 pm to 7 pm, on Saturday from 9 am to 1:30 pm and 2 pm to 5 pm, and on Sunday from 11 am to 1:30 pm and 2 pm to 5 pm. Reviewers mention pharmacists who correct errors professionally, timely refills and a smaller store located inside a Target.
Best for: Refills and professional service
- Address
- 333 N 48th St, Lincoln, NE 68504, United States
- Hours
- Fri 9 am–1:30 pm, 2–7 pm; Mon 9 am–1:30 pm, 2–7 pm; Sat 9 am–1:30 pm, 2–5 pm; Sun 11 am–1:30 pm, 2–5 pm; Thu 9 am–1:30 pm, 2–7 pm; Tue 9 am–1:30 pm, 2–7 pm; Wed 9 am–1:30 pm, 2–7 pm
#5
CVS Pharmacy
★ 4.5 (56 Google reviews)Pharmacy
Representative photo, not of this business.
CVS Pharmacy at 1550 South St is rated 4.5 from 56 reviews. It is open Monday to Friday from 9 am to 1:30 pm and 2 pm to 8 pm, on Saturday from 9 am to 1:30 pm and 2 pm to 6 pm, and on Sunday from 10 am to 1:30 pm and 2 pm to 6 pm.
Best for: Package pickup and cost-saving help
- Address
- 1550 South St, Lincoln, NE 68502, United States
- Hours
- Fri 9 am–1:30 pm, 2–8 pm; Mon 9 am–1:30 pm, 2–8 pm; Sat 9 am–1:30 pm, 2–6 pm; Sun 10 am–1:30 pm, 2–6 pm; Thu 9 am–1:30 pm, 2–8 pm; Tue 9 am–1:30 pm, 2–8 pm; Wed 9 am–1:30 pm, 2–8 pm
How we made this list
We looked at 13 pharmacies in Downtown, Lincoln NE with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, Lincoln Pharmacy opens at 8:30 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated pharmacy on this list?
Lincoln Pharmacy ranks first, with a Google rating of 4.7 from 67 reviews. Pharmacy Solutions is second at 4.6 from 95 reviews.
Which pharmacies in Downtown, Lincoln NE are open late?
None of these stays open past midnight. The latest to close is CVS Pharmacy, at 8 pm.
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