5 Best Pharmacies in Downtown, Lawrence KS
Updated 11 October 2026 · 6 pharmacies in Downtown, Lawrence KS considered · Ranked from Google ratings
This list ranks six qualifying pharmacies in or near Downtown Lawrence, KS by Google rating, weighted by how many people left a review. Two Sigler Pharmacy locations appear as separate listings. One entry, Downtown Drug Store, has a Tonganoxie, KS address, so check the address before visiting. Each entry gives listed hours and attributes, followed by themes that reviewers mention, including both praise and complaints.
#1
Sigler Pharmacy - 6th Street
★ 4.8 (58 Google reviews)Pharmacy
Representative photo, not of this business.
Sigler Pharmacy - 6th Street is listed at 4525 W 6th St, Suite 104, Lawrence, KS 66049, with a 4.8 rating from 58 reviews. Hours are Monday through Friday 8 am to 6 pm and Saturday 9 am to 2 pm, with Sunday closed. Google lists wheelchair-accessible parking and entrance. Reviewers mention staff who remember names, help resolving a communication problem with a doctor's office, friendly recommendations, and a transfer from another pharmacy that went smoothly. One reviewer calls it locally owned with personal service.
Best for: Personal service and prescription transfers
- Address
- 4525 W 6th St Suite 104, Lawrence, KS 66049, United States
- Hours
- Fri 8 am–6 pm; Mon 8 am–6 pm; Sat 9 am–2 pm; Sun Closed; Thu 8 am–6 pm; Tue 8 am–6 pm; Wed 8 am–6 pm
#2
Jayhawk Pharmacy
★ 5 (33 Google reviews)Pharmacy
Representative photo, not of this business.
Jayhawk Pharmacy is listed at 3510 Clinton Pkwy Pl, Suite 200, Lawrence, KS 66047, with a 5 rating from 33 reviews. Hours are Monday through Friday 8:30 am to 5:30 pm and Saturday 9 am to noon, with Sunday closed. Google lists wheelchair-accessible parking and entrance. Reviewers mention help organizing pills for a relative, delivery to an independent living home, calls when prescriptions are ready, and a long-time customer praising the staff for personal attention. One reviewer switched from a national chain for the updates.
Best for: Pill organizing and home delivery
- Address
- 3510 Clinton Pkwy Pl #200, Lawrence, KS 66047, United States
- Hours
- Fri 8:30 am–5:30 pm; Mon 8:30 am–5:30 pm; Sat 9 am–12 pm; Sun Closed; Thu 8:30 am–5:30 pm; Tue 8:30 am–5:30 pm; Wed 8:30 am–5:30 pm
#3
Sigler Pharmacy - Downtown Lawrence
★ 4.4 (50 Google reviews)Pharmacy
Representative photo, not of this business.
Sigler Pharmacy - Downtown Lawrence is listed at 1046 Vermont St, Lawrence, KS 66044, with a 4.4 rating from 50 reviews. Hours match the 6th Street location: weekdays 8 am to 6 pm and Saturday 9 am to 2 pm, with Sunday closed. Google lists wheelchair-accessible parking and entrance. Reviewers mention staff who gathered over-the-counter supplies and matched them to a list, and staff who accommodate specific needs. Others describe a long wait when a prescription was sent to the wrong place, and one says insurance was not accepted on a transferred prescription.
Best for: Over-the-counter help near Vermont Street
- Address
- 1046 Vermont St, Lawrence, KS 66044, United States
- Hours
- Fri 8 am–6 pm; Mon 8 am–6 pm; Sat 9 am–2 pm; Sun Closed; Thu 8 am–6 pm; Tue 8 am–6 pm; Wed 8 am–6 pm
#4
Downtown Drug Store
★ 4.5 (25 Google reviews)Pharmacy
Representative photo, not of this business.
Downtown Drug Store is listed at 516 E 4th St, Tonganoxie, KS 66086, which is outside Lawrence, so confirm the address before visiting. It is rated 4.5 from 25 reviews. Hours are Monday through Friday 9 am to 6 pm and Saturday 9 am to noon, with Sunday closed. Google lists delivery, kerbside pickup, medication disposal, and a small business label. Reviewers mention prescriptions filled quickly, staff who worked on a way to fill an expensive new prescription, and knowledgeable, friendly service.
Best for: Fast fills and a small-town feel
- Address
- 516 E 4th St, Tonganoxie, KS 66086, United States
- Hours
- Fri 9 am–6 pm; Mon 9 am–6 pm; Sat 9 am–12 pm; Sun Closed; Thu 9 am–6 pm; Tue 9 am–6 pm; Wed 9 am–6 pm
#5
Dillons Pharmacy
★ 4.2 (26 Google reviews)Pharmacy
Representative photo, not of this business.
Dillons Pharmacy is listed at 1740 Massachusetts St, Lawrence, KS 66044, with a 4.2 rating from 26 reviews. Hours are weekdays 9 am to 1 pm and 1:30 to 8 pm, Saturday 9 am to 1 pm and 1:30 to 6 pm, and Sunday 11 am to 1 pm and 1:30 to 6 pm. Google lists wheelchair-accessible parking, entrance, seating, and restroom. Reviewers mention autofill, text message alerts, and staff who answer questions. Other reviewers are critical of professionalism at this store, so experiences vary.
Best for: Autofill and text refill alerts
- Address
- 1740 Massachusetts St, Lawrence, KS 66044, United States
- Hours
- Fri 9 am–1 pm, 1:30–8 pm; Mon 9 am–1 pm, 1:30–8 pm; Sat 9 am–1 pm, 1:30–6 pm; Sun 11 am–1 pm, 1:30–6 pm; Thu 9 am–1 pm, 1:30–8 pm; Tue 9 am–1 pm, 1:30–8 pm; Wed 9 am–1 pm, 1:30–8 pm
How we made this list
We looked at 6 pharmacies in Downtown, Lawrence KS with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, Sigler Pharmacy - 6th Street opens at 8 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated pharmacy on this list?
Sigler Pharmacy - 6th Street ranks first, with a Google rating of 4.8 from 58 reviews. Jayhawk Pharmacy is second at 5 from 33 reviews.
Which pharmacies in Downtown, Lawrence KS are open late?
None of these stays open past midnight. The latest to close is Dillons Pharmacy, at 8 pm.
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