5 Best Dental Clinics in Greenville SC
Updated 11 October 2026 · 14 dental clinics in Greenville SC considered · Ranked from Google ratings
This guide lists five dental clinics in Greenville SC for people choosing a dentist, whether they want a new practice, a comfortable place for anxious visits, or a clinic that can see them quickly. Practices are ranked by Google rating weighted by review count, with a 300-review minimum. Fourteen qualifying businesses were considered. Each entry covers hours, location, listed services, and what patients mention in their reviews.
#1
West End Dental
★ 5 (758 Google reviews)Dentist
Representative photo, not of this business.
West End Dental is a dental office on South Main Street with a 5 rating from 758 reviews. It is open Monday through Thursday from 8 am to 5 pm, Friday from 8 am to 2 pm, and closed on weekends. Google lists cosmetic dentistry, pediatric care, and sedation dentistry, along with a free parking lot. Patients mention a calm, stress-free visit, a hygienist who takes extra time, and quick help when they arrive with an urgent problem.
Best for: Cosmetic, pediatric, and sedation care
- Address
- 655 S Main St, Greenville, SC 29601, United States
- Hours
- Fri 8 am–2 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–5 pm; Tue 8 am–5 pm; Wed 8 am–5 pm
#2
Gilbert Dental Group
★ 5 (479 Google reviews)Dentist
Representative photo, not of this business.
Gilbert Dental Group is a dentist on Cleveland Street with a 5 rating from 479 reviews. Hours are Monday, Tuesday, and Wednesday from 8:30 am to 5 pm, Thursday from 7 am to 5 pm, and the office is closed Friday through Sunday. Google lists wheelchair-accessible parking, entrance, and toilet. Patients describe a team that explains each step, a comfortable atmosphere for people with anxiety, and fast scheduling for new patients who need an appointment soon.
Best for: Nervous and new patients
- Address
- 870 Cleveland St, Greenville, SC 29601, United States
- Hours
- Fri Closed; Mon 8:30 am–5 pm; Sat Closed; Sun Closed; Thu 7 am–5 pm; Tue 8:30 am–5 pm; Wed 8:30 am–5 pm
#3
Choice One Dental Care of Greenville
★ 5 (430 Google reviews)Dentist
Representative photo, not of this business.
Choice One Dental Care of Greenville is a dentist on Cleveland Court with a 5 rating from 430 reviews. It is open Monday, Tuesday, and Wednesday from 8 am to 5 pm, Friday from 8 am to 1 pm, and on Thursday from 8 am to 1 pm and 2 to 5 pm. It is closed Saturday and Sunday. Google lists emergency services and cosmetic dentistry. Patients mention a spotless office, a team that works in urgent cases, and short waits for those who book a set time.
Best for: Urgent visits and cosmetic work
- Address
- 5C Cleveland Ct, Greenville, SC 29607, United States
- Hours
- Fri 8 am–1 pm; Mon 8 am–5 pm; Sat Closed; Sun Closed; Thu 8 am–1 pm, 2–5 pm; Tue 8 am–5 pm; Wed 8 am–5 pm
#4
Greenville Family Smiles
★ 5 (396 Google reviews)Dentist
Representative photo, not of this business.
Greenville Family Smiles is a dental office on Parkins Mill Road with a 5 rating from 396 reviews. It is open Monday through Thursday from 8:30 am to 5 pm and Friday from 8:30 am to 2 pm, and closed on weekends. Google lists wheelchair-accessible parking, entrance, and toilet. Patients say the team is patient with severe dental anxiety, helps with insurance questions, and offers flexible payment and financing options for larger treatment plans.
Best for: Patients with dental anxiety
- Address
- 6 Parkins Mill Rd, Greenville, SC 29607, United States
- Hours
- Fri 8:30 am–2 pm; Mon 8:30 am–5 pm; Sat Closed; Sun Closed; Thu 8:30 am–5 pm; Tue 8:30 am–5 pm; Wed 8:30 am–5 pm
#5
Rocky Creek Dental Care - Greenville
★ 5 (330 Google reviews)Dentist
Representative photo, not of this business.
Rocky Creek Dental Care - Greenville is a dental practice on East Washington Street with a 5 rating from 330 reviews. It is open Monday through Thursday from 7:30 am to 5 pm, Friday from 7:30 am to 3 pm, and closed on weekends. Google lists wheelchair-accessible parking, entrance, and toilet. Long-term patients describe thorough and thoughtful dentists, an office that avoids pushing extra products, and easy scheduling for routine cleanings.
Best for: Long-term family care and cleanings
- Address
- 1322 E Washington St # D1, Greenville, SC 29607, United States
- Hours
- Fri 7:30 am–3 pm; Mon 7:30 am–5 pm; Sat Closed; Sun Closed; Thu 7:30 am–5 pm; Tue 7:30 am–5 pm; Wed 7:30 am–5 pm
How we made this list
We looked at 14 dental clinics in Greenville SC with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by weighted Google rating across the city, 300 reviews minimum. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, Gilbert Dental Group opens at 7 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated dental clinic on this list?
West End Dental ranks first, with a Google rating of 5 from 758 reviews. Gilbert Dental Group is second at 5 from 479 reviews.
Which dental clinics in Greenville SC are open late?
None of these stays open past midnight. The latest to close is West End Dental, at 5 pm.
Which of these have free parking?
Google lists free parking for West End Dental.
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