5 Best Pharmacies in Downtown, Corpus Christi TX
Updated 11 October 2026 · 11 pharmacies in Downtown, Corpus Christi TX considered · Ranked from Google ratings
This list covers pharmacies in Downtown, Corpus Christi TX, including grocery stores whose Google listings include a pharmacy. Eleven qualifying businesses were considered, and they were ranked by Google rating, weighted by how many people reviewed each one. The five below are shown in ranked order. Each entry lists hours, address and features such as pick-up, delivery and wheelchair access, with notes from public reviews. Hours change, so confirm current opening times before visiting.
#1
H-E-B plus!
★ 4.6 (5,083 Google reviews)Grocery store
Representative photo, not of this business.
H-E-B plus! is a grocery store with a 4.6 rating from 5,083 Google reviews. It is open daily from 6 am to 11 pm at 5313 Saratoga Blvd. Google lists a pharmacy, curbside pickup, delivery, no-contact delivery, great produce, organic products, prepared foods, Wi-Fi and a free parking lot. Reviewers mention strong customer service, frequent sales and a wide selection of name brands and store brands. A few reviewers raised concerns about a curbside order with an inaccurate weight.
Best for: Groceries and pharmacy in one stop
- Address
- 5313 Saratoga Blvd, Corpus Christi, TX 78413, United States
- Hours
- daily 6 am–11 pm
#2
H-E-B
★ 4.6 (2,196 Google reviews)Grocery store
Representative photo, not of this business.
H-E-B is a grocery store with a 4.6 rating from 2,196 Google reviews. It is open daily from 6 am to 11 pm at 4320 S Alameda St. Google lists a pharmacy, curbside pickup, delivery, SNAP/EBT, prepared foods, great produce and a free parking lot. Reviewers mention a clean, well-stocked store with prices in line with other grocers. Other reviewers raised a curbside fee complaint and a concern about cleanliness in a cooler.
Best for: Full grocery run with pharmacy access
- Address
- 4320 S Alameda St, Corpus Christi, TX 78412, United States
- Hours
- daily 6 am–11 pm
#3
Nichols Southside Pharmacy
★ 4.7 (39 Google reviews)Pharmacy
Representative photo, not of this business.
Nichols Southside Pharmacy has a 4.7 rating from 39 Google reviews. It is open Monday to Friday from 9 am to 6 pm and Saturday from 9 am to noon, with Sunday closed. The address is 3141 Gollihar Rd. Google lists wheelchair-accessible parking and entrance. Reviewers mention patient, professional staff, a family-owned feel and items beyond prescriptions, such as orthopedic shoes and gifts. One reviewer said they wished it were open on weekends.
Best for: Friendly service and a neighborhood feel
- Address
- 3141 Gollihar Rd, Corpus Christi, TX 78415, United States
- Hours
- Fri 9 am–6 pm; Mon 9 am–6 pm; Sat 9 am–12 pm; Sun Closed; Thu 9 am–6 pm; Tue 9 am–6 pm; Wed 9 am–6 pm
#4
CVS Pharmacy
★ 4.7 (26 Google reviews)Pharmacy
Representative photo, not of this business.
CVS Pharmacy has a 4.7 rating from 26 Google reviews. It keeps a midday break on weekdays, with Saturday hours from 10 am to 6 pm and Sunday from 11 am to 5 pm. The address is 7798 S Padre Island Dr. Google lists delivery, drive-through, in-store pick-up, medication disposal, naloxone, passport photos and SNAP/EBT. Reviewers mention pharmacists who explain medications in plain language and a clean, well-stocked store. Some describe the pharmacy as busy and understaffed at times.
Best for: Drive-through and in-store prescription pick-up
- Address
- 7798 S Padre Island Dr, Corpus Christi, TX 78412, United States
- Hours
- Fri 9 am–1:30 pm, 2–7 pm; Mon 9 am–1:30 pm, 2–7 pm; Sat 10 am–1:30 pm, 2–6 pm; Sun 11 am–1:30 pm, 2–5 pm; Thu 9 am–1:30 pm, 2–7 pm; Tue 9 am–1:30 pm, 2–7 pm; Wed 9 am–1:30 pm, 2–7 pm
#5
H-E-B
★ 4.3 (2,085 Google reviews)Grocery store
Representative photo, not of this business.
H-E-B has a 4.3 rating from 2,085 Google reviews. It is open daily from 7 am to 10 pm at 3500 Leopard St. Google lists a pharmacy, delivery, wheelchair-accessible seating, Wi-Fi, SNAP/EBT, great produce and paid parking. Reviewers mention quick, efficient service in a smaller store and a visible security presence. Some reviewers warn that two H-E-B stores share Leopard Street, so check the address first. Others report shelves running low on staple items.
Best for: Quick trips to a smaller store
- Address
- 3500 Leopard St, Corpus Christi, TX 78408, United States
- Hours
- daily 7 am–10 pm
How we made this list
We looked at 11 pharmacies in Downtown, Corpus Christi TX with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, H-E-B plus! opens at 6 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated pharmacy on this list?
H-E-B plus! ranks first, with a Google rating of 4.6 from 5,083 reviews. H-E-B is second at 4.6 from 2,196 reviews.
Which pharmacies in Downtown, Corpus Christi TX are open late?
None of these stays open past midnight. The latest to close is H-E-B plus!, at 11 pm.
Which of these have free parking?
Google lists free parking for H-E-B plus! and H-E-B.
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