5 Best Pharmacies in Downtown, Charleston WV
Updated 11 October 2026 · 8 pharmacies in Downtown, Charleston WV considered · Ranked from Google ratings
This list covers five pharmacies serving the Downtown Charleston WV area, ranked by Google rating weighted by how many people left a review. We considered 8 qualifying businesses. Some locations sit in nearby neighborhoods such as Sissonville and South Charleston, so check the address and hours before a visit. Each entry lists services, accessibility and what reviewers mention, including prescription speed, stock levels, customer service and cost help, so you can choose the counter that fits your needs.
#1
Kines Family Pharmacy
★ 4.8 (29 Google reviews)Pharmacy
Representative photo, not of this business.
Kines Family Pharmacy is a small pharmacy on Sissonville Drive rated 4.8 from 29 Google reviews. It is open Monday through Friday from 9 am to 7 pm and closed on weekends. The listing shows delivery, in-store shopping, medication disposal, and wheelchair-accessible parking and entrance. Reviewers mention fast, friendly service and staff who look for medicines elsewhere when they are not in stock. One reviewer raised a concern about prior authorization notices.
Best for: Local service and medication disposal
- Address
- 6097 Sissonville Dr, Charleston, WV 25312, United States
- Hours
- Fri 9 am–7 pm; Mon 9 am–7 pm; Sat Closed; Sun Closed; Thu 9 am–7 pm; Tue 9 am–7 pm; Wed 9 am–7 pm
#2
Walgreens Pharmacy
★ 4.6 (21 Google reviews)Pharmacy
Representative photo, not of this business.
Walgreens Pharmacy on Sissonville Drive is rated 4.6 from 21 Google reviews. Hours run Monday through Friday with a midday break, Saturday until 6 pm, and Sunday closed. The listing shows wheelchair-accessible parking and an entrance. Reviewers mention a friendly and knowledgeable pharmacist, medicines that are usually in stock, and prescriptions filled in a timely way. It suits people who want a dependable place for regular refills.
Best for: Reliable refills and in-stock medicines
- Address
- 6401 Sissonville Dr, Charleston, WV 25312, United States
- Hours
- Fri 9 am–1:30 pm, 2–8 pm; Mon 9 am–1:30 pm, 2–8 pm; Sat 9 am–1:30 pm, 2–6 pm; Sun Closed; Thu 9 am–1:30 pm, 2–8 pm; Tue 9 am–1:30 pm, 2–8 pm; Wed 9 am–1:30 pm, 2–8 pm
#3
CVS Pharmacy
★ 4.5 (26 Google reviews)Pharmacy
Representative photo, not of this business.
CVS Pharmacy on RHL Boulevard in South Charleston is rated 4.5 from 26 Google reviews. It is open seven days, including Sunday afternoons, with a midday pause on most days. The listing shows delivery, in-store shopping, medication disposal, naloxone, quick visits and card payments. Reviewers mention strong customer service, staff who know regulars by name, short waits, and calls when prescriptions are ready.
Best for: Sunday hours and quick visits
- Address
- 30 RHL Blvd, South Charleston, WV 25309, United States
- Hours
- Fri 9 am–1:30 pm, 2–7 pm; Mon 9 am–1:30 pm, 2–7 pm; Sat 9 am–1:30 pm, 2–5 pm; Sun 11 am–1:30 pm, 2–5 pm; Thu 9 am–1:30 pm, 2–7 pm; Tue 9 am–1:30 pm, 2–7 pm; Wed 9 am–1:30 pm, 2–7 pm
#4
Clark's Family Pharmacy
★ 4.4 (36 Google reviews)Pharmacy
Representative photo, not of this business.
Clark's Family Pharmacy on MacCorkle Avenue SW in South Charleston is rated 4.4 from 36 Google reviews. Hours run Monday to Friday from 9 am to 7 pm and Saturday until 2 pm, with Sunday closed. The listing shows wheelchair-accessible parking and an entrance. Reviewers mention respectful staff, medications ready on time, and extra effort when a supply problem arose. Some reviewers were less satisfied with the range of medications available in pill packs.
Best for: Respectful staff and on-time refills
- Address
- 4501 MacCorkle Ave SW Ste 101, South Charleston, WV 25309, United States
- Hours
- Fri 9 am–7 pm; Mon 9 am–7 pm; Sat 9 am–2 pm; Sun Closed; Thu 9 am–7 pm; Tue 9 am–7 pm; Wed 9 am–7 pm
#5
Walmart Pharmacy
★ 4.4 (24 Google reviews)Pharmacy
Representative photo, not of this business.
Walmart Pharmacy on Mountaineer Boulevard in South Charleston is rated 4.4 from 24 Google reviews. It is open daily, with shorter Sunday hours from 10 am to 6 pm. The listing shows wheelchair-accessible parking, an entrance and a restroom. Reviewers mention reliable stock, quick help when people arrive before prescriptions are ready, and easy transfers for people who travel. One reviewer said staff found a lower price when insurance did not cover a medication.
Best for: Stock on hand and cost help
- Address
- 2700 Mountaineer Blvd, South Charleston, WV 25309, United States
- Hours
- Fri 9 am–7 pm; Mon 9 am–7 pm; Sat 9 am–7 pm; Sun 10 am–6 pm; Thu 9 am–7 pm; Tue 9 am–7 pm; Wed 9 am–7 pm
How we made this list
We looked at 8 pharmacies in Downtown, Charleston WV with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, Kines Family Pharmacy opens at 9 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated pharmacy on this list?
Kines Family Pharmacy ranks first, with a Google rating of 4.8 from 29 reviews. Walgreens Pharmacy is second at 4.6 from 21 reviews.
Which pharmacies in Downtown, Charleston WV are open late?
None of these stays open past midnight. The latest to close is Walgreens Pharmacy, at 8 pm.
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