5 Best Clinics in Charleston SC
Updated 11 October 2026 · 14 clinics in Charleston SC considered · Ranked from Google ratings
This list covers five clinics in Charleston SC that locals and visitors can use for urgent care and primary care. Businesses were ranked by Google rating weighted by review count, with a minimum of 300 reviews. Fourteen qualifying businesses were considered before the top five were selected. Each entry notes the clinic type, hours, address, listed services, and what reviewers mention, so you can pick the right fit whether you need walk-in care, an appointment, or a regular doctor.
#1
Access Urgent
★ 4.9 (879 Google reviews)Urgent care center
Representative photo, not of this business.
Access Urgent is an urgent care center at 233 Calhoun St in Charleston, open daily from 8 am to 8 pm. It holds a 4.9 Google rating from 879 reviews and lists on-site services, walk-ins, and appointments as options. Google attributes note wheelchair-accessible parking, entrance, and restroom, along with free and paid parking nearby. Reviewers mention a quick visit, friendly front desk and provider staff, and care for stitches and minor procedures, with one visitor saying they were in and out in about 30 minutes.
Best for: Walk-in urgent care with on-site services
- Address
- 233 Calhoun St, Charleston, SC 29401, United States
- Hours
- daily 8 am–8 pm
#2
Roper St. Francis Physician Partners Primary Care
★ 4.9 (511 Google reviews)Medical group
Representative photo, not of this business.
Roper St. Francis Physician Partners Primary Care is a medical group at 615 Wesley Dr in Charleston. It holds a 4.9 Google rating from 511 reviews and is open Monday through Friday from 9 am to 5 pm, closed on weekends. Appointments are required or recommended, and the office accepts cards and NFC payments. Wheelchair-accessible parking, entrance, and restroom are listed. Several reviewers describe the physicians as their regular primary care doctors who are thorough, listen closely, and explain decisions clearly.
Best for: Ongoing primary care with appointments
- Address
- 615 Wesley Dr Ste. 200, Charleston, SC 29407, United States
- Hours
- Fri 9 am–5 pm; Mon 9 am–5 pm; Sat Closed; Sun Closed; Thu 9 am–5 pm; Tue 9 am–5 pm; Wed 9 am–5 pm
#3
HCA CareNow - Mt. Pleasant
★ 4.8 (2,777 Google reviews)Urgent care center
Representative photo, not of this business.
HCA CareNow in Mount Pleasant is an urgent care center at 2863 N Hwy 17 with a 4.8 Google rating from 2,777 reviews. It is open daily from 8 am to 8 pm and accepts walk-ins. Listed services include X-ray, pediatric care, and IV therapy. Reviewers praise attentive staff and capable nurses, and some say they joined the queue online before leaving home. Others find the registration process long and report a lengthy wait at check-in, so arriving with time to spare may help.
Best for: Urgent care with X-ray and IV therapy
- Address
- 2863 N Hwy 17, Mt Pleasant, SC 29466, United States
- Hours
- daily 8 am–8 pm
#4
Prisma Health Urgent Care–Mount Pleasant North
★ 4.9 (303 Google reviews)Urgent care center
Representative photo, not of this business.
Prisma Health Urgent Care in Mount Pleasant North sits at 1101 Greythorne Dr and is open daily from 8 am to 8 pm. It holds a 4.9 Google rating from 303 reviews. Appointments are required, and reviewers describe online scheduling and registration as easy. The listing also notes wheelchair-accessible parking, entrance, and restroom. Reviewers describe the facility as clean and new, a friendly front desk, triage nurses who were excellent, and a physician who handled a painful cyst. One family said a child enjoyed visiting the front office staff.
Best for: Newer urgent care with online scheduling
- Address
- 1101 Greythorne Dr, Mt Pleasant, SC 29466, United States
- Hours
- daily 8 am–8 pm
#5
Holy City Med Primary and Urgent Care (North Charleston)
★ 4.8 (667 Google reviews)Medical Center
Representative photo, not of this business.
Holy City Med Primary and Urgent Care is a medical center at 5479 N Rhett Ave in North Charleston, open Monday through Friday from 8 am to 8 pm and Saturday from 8 am to 5 pm. It holds a 4.8 Google rating from 667 reviews. The listing notes wheelchair-accessible parking, entrance, and restroom. Reviewers mention doctors who take time to listen and answer questions, intake staff who make check-in quick, and staff who were kind during an urgent visit. Some describe the practice as both primary and urgent care in one place.
Best for: Primary and urgent care with unhurried visits
- Address
- 5479 N Rhett Ave, North Charleston, SC 29406, United States
- Hours
- Fri 8 am–8 pm; Mon 8 am–8 pm; Sat 8 am–5 pm; Sun Closed; Thu 8 am–8 pm; Tue 8 am–8 pm; Wed 8 am–8 pm
How we made this list
We looked at 14 clinics in Charleston SC with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by weighted Google rating across the city, 300 reviews minimum. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- For an early start, Access Urgent opens at 8 am.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated clinic on this list?
Access Urgent ranks first, with a Google rating of 4.9 from 879 reviews. Roper St. Francis Physician Partners Primary Care is second at 4.9 from 511 reviews.
Which clinics in Charleston SC are open late?
None of these stays open past midnight. The latest to close is Access Urgent, at 8 pm.
Which of these have free parking?
Google lists free parking for Access Urgent.
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